RTx-161

Name: RTx-161
Brand: QuantiMol
SKU: QM-0153167-01
Price: 1079.11 GBP
Availability: InStock

Size 1 mg 5 mg

SKU:QM-0153167-01

£1,079.11 GBP

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Product Details

Description
RTx-161 is an allosteric Polθ polymerase inhibitor with an IC50 value of 4.1 nM. RTx-161 selectively kills HR-deficient cancer cells and suppresses PARP inhibitor (PARPi) resistance in multiple genetic backgrounds, including HR-proficient cells. Additionally, RTx-161 can induce apoptosis[1].
Molecular Formula
C21H18F7N3O4
Molecular Weight
509.37
Smiles
FC(F)(F)C1=CC(N2CCN(CCO)C2=O)=C(OC(N(C3=CC=C(F)C=C3)C)=O)C(C(F)(F)F)=C1
Target
Apoptosis; DNA/RNA Synthesis
Purity
98
Solubility
10 mM in DMSO
Storage Conditions
4°C (Powder, protect from light)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0153167-01	1 mgQM-0153167-01 £1,079.11/ea	£0.00	Quantity	£1,079.11/ea	£0.00

5 mgQM-0153167-02	5 mgQM-0153167-02 £3,162.83/ea	£0.00	Quantity	£3,162.83/ea	£0.00

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RTx-161 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.