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RU.521 [CAS 2262452-06-0]

RU.521 [CAS 2262452-06-0]

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QM-0138309-01

£200.66 GBP
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Product Details

  • Description

    RU.521 (RU320521) is a potent and selective cyclic GMP-AMP synthase (cGAS) inhibitor and inhibits cGAS-mediated interferon upregulation. RU.521 suppresses dsDNA-activated reporter activity with an IC50 of 0.7 μM. RU.521 reduces constitutive expression of interferon in macrophages from a mouse model of Aicardi-Goutières syndrome (AGS) [1].

  • CAS Number

    [2262452-06-0]

  • Molecular Formula

    C19H12Cl2N4O3

  • Molecular Weight

    415.23

  • Smiles

    O=C1OC(C2=C(O)N(C3=NC4=CC=C(Cl)C(Cl)=C4N3)N=C2C)C5=C1C=CC=C5

  • Target

    Cyclic GMP-AMP Synthase

  • Purity

    99.95

  • Solubility

    DMSO : 83.33 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
5 mgQM-0138309-01
5 mgQM-0138309-01
£200.66/ea		 £0.00
£200.66/ea £0.00
10 mgQM-0138309-02
10 mgQM-0138309-02
£275.99/ea		 £0.00
£275.99/ea £0.00
25 mgQM-0138309-03
25 mgQM-0138309-03
£470.39/ea		 £0.00
£470.39/ea £0.00
50 mgQM-0138309-04
50 mgQM-0138309-04
£646.57/ea		 £0.00
£646.57/ea £0.00
100 mgQM-0138309-05
100 mgQM-0138309-05
£928.45/ea		 £0.00
£928.45/ea £0.00
500 mgQM-0138309-06
500 mgQM-0138309-06
£2,246.72/ea		 £0.00
£2,246.72/ea £0.00
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RU.521 [CAS 2262452-06-0]

RU.521 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.