[Ru (phen) 2 (4-Me-Sal) ]BF4

[Ru (phen) 2 (4-Me-Sal) ]BF4 (compound 10), a Ru (II) -based polypyridyl complexe, displays outstanding antiproliferative activity against drug-sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells (IC50=0.52 μM and 5.56 μM, respectively) [1].

C32H23BF4N4O2Ru-

683.43

CC1=CC(O[Ru]23([N]4=C5C(C=CC6=C5[N]2=CC=C6)=CC=C4)([N]7=CC=CC8=C7C9=[N]3C=CC=C9C=C8)O=C%10)=C%10C=C1.[F-][B+3]([F-])([F-])[F-].[+]

Others

10 mM in DMSO

Room temperature