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Ruxolitinib (sulfate) [CAS 1092939-16-6]
Ruxolitinib (sulfate) [CAS 1092939-16-6]
SKU:QM-0000732
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Product Details
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Description
Ruxolitinib sulfate (INCB018424 sulfate) is the first potent, selective JAK1/2 inhibitor to enter the clinic with IC50s of 3.3 nM/2.8 nM, and has > 130-fold selectivity for JAK1/2 versus JAK3.
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CAS Number
[1092939-16-6]
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Molecular Formula
C17H20N6O4S
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Molecular Weight
404.44
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Smiles
[H][C@@](C1CCCC1)(N2N=CC(C3=C4C=CNC4=NC=N3)=C2)CC#N.O=S(O)(O)=O
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Target
Autophagy; JAK
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Isoform
JAK1; JAK2; JAK3; Tyk2
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Purity
98.26
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Ruxolitinib (sulfate) [CAS 1092939-16-6]
Ruxolitinib (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.