RWT9996 [CAS 2877694-62-5]

RWT9996 is a balanced GPR17 antagonist. RWT9996 has an inhibitory effect on G protein activation and β-arrestin-2 recruitment induced by MDL-29951. RWT9996 inhibits the phosphorylation of ERK/CREB and the accumulation of inositol phosphate (b IP1) induced by MDL-29951. RWT9996 can be used for the study of neurological diseases[1].

[2877694-62-5]

C17H12FN3O2S

341.36

FC1=C(NS(C2=CNC(C3=CC=CC=C3)=C2)(=O)=O)C=CC(C#N)=C1

Arrestin; Epigenetic Reader Domain; ERK; Transmembrane Glycoprotein

Room temperature