(S) -AZD 6482 [CAS 1173900-37-2]

(S) -AZD6482 ((S) -KIN-193) is a highly effective and selective ATP-competitive inhibitor of PI3Kβ, exhibiting an IC (50) of 0.01 μM, and it can reduce insulin-induced glucose uptake by human adipocytes in vitro with an IC (50) of 4.4 μM.

[1173900-37-2]

C22H24N4O4

408.45

O=C(C1=CC=CC=C1N[C@@H](C)C2=CC(C)=CN3C2=NC(N4CCOCC4)=CC3=O)O

PI3K

Room temperature

H302-H315-H320-H335

P261-P280-P302+P352