(S) -GSK-3685032 [CAS 2170142-58-0]
(S) -GSK-3685032 [CAS 2170142-58-0]
SKU:QM-0146823-01
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Product Details
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Description
(S) -GSK-3685032 is the isomer of GSK-3685032 , and can be used as an experimental control. GSK-3685032 is a non-time-dependent, noncovalently, first-in-class reversible DNMT1-selective inhibitor, with an IC50 of 0.036 μM. GSK-3685032 induces robust loss of DNA methylation, transcriptional activation, and cancer cell growth inhibition[1].
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CAS Number
[2170142-58-0]
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Molecular Formula
C22H24N6OS
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Molecular Weight
420.53
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Smiles
N#CC1=C(N2CCC(CC2)N)N=C(C(C#N)=C1CC)S[C@@H](C3=CC=CC=C3)C(N)=O
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Target
DNA Methyltransferase
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Purity
98.82
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Solubility
DMSO : 90 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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(S) -GSK-3685032 [CAS 2170142-58-0]
(S) -GSK-3685032 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.