(S) -GSK-F1 [CAS 1384097-27-1]
(S) -GSK-F1 [CAS 1384097-27-1]
SKU:QM-0079498-01
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Product Details
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Description
(S) -GSK-F1 (Compound 28) is an inhibitor for type III phosphatidylinositol 4-kinase α (PI4KIIIα) . (S) -GSK-F1 inhibits PI4Kα, PI4Kβ, PI4Kγ, PI3Kα, PI3Kβ and PI3Kδ with pIC50 of 8.3, 6.0, 5.6, 5.6, 5.1 and 5.6, respectively. (S) -GSK-F1 exhibits anti-hepatitis C virus (HCV) activity through inhibition of HCV replication. (S) -GSK-F1 exhibits moderate pharmacokinetic characters in rat model[1].
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CAS Number
[1384097-27-1]
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Molecular Formula
C27H18F5N5O4S
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Molecular Weight
603.52
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Smiles
O=C1C2=C(N=C(N1C3=CC=CC=C3C(F)(F)F)N)C=CC(C4=CC(S(=O)(NC5=CC=C(C=C5F)F)=O)=C(OC)N=C4)=C2
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Target
PI3K; PI4K
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Isoform
PI3Kα; PI3Kβ; PI3Kδ; PI4KIIIα; PI4KIIIβ
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Purity
98.01
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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(S) -GSK-F1 [CAS 1384097-27-1]
(S) -GSK-F1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.