(S) -NDT-19795

(S) -NDT-19795 is a potent NLRP3 inflammasome inhibitor. (S) -NDT-19795 blocks NLRP3 activation by inhibiting NLRP3 ATPase activity, thereby reducing the levels of pro-inflammatory cytokines IL-1β and IL-18. (S) -NDT-19795 can be used in the study of neurodegenerative diseases, cardiovascular diseases, metabolic diseases, and autoimmune diseases[1].

C20H21N3O4

367.4

OC([C@H](CC1=NC=CC=N1)OC(NC2=C3C(CCC3)=CC4=C2CCC4)=O)=O

NOD-like Receptor (NLR)

Room temperature