(S) -Norzopiclone [CAS 151776-26-0]

(S) -Norzopiclone ((S) -N-Desmethyl zopiclone; SEP-174559) is a metabolite of Zopiclone with anxiolytic and anticonvulsant effects. (S) -Norzopiclone has benzodiazepine-like actions at γ2-bearing subtypes of the GABAA receptor and inhibits nACh and NMDA receptors[1].

[151776-26-0]

C16H15ClN6O3

374.78

O=C(O[C@@H]1N(C(C2=NC=CN=C21)=O)C3=NC=C(C=C3)Cl)N4CCNCC4

GABA Receptor; iGluR; nAChR

10 mM in DMSO

Room temperature