(S) -PF-04449613

(S) -PF-04449613 is the left-handed isomer of PF-04449613. PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM. PF-04449613 improves motor learning ability in a mouse model[1][2].

C21H25N5O3

395.45

O=C1C2=C(NC([C@@H](N3CC(C3)OC4=CC=CC=C4)C)=N1)N(C5CCOCC5)N=C2

Phosphodiesterase (PDE)

99.85

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature