(S) -Phe-A110/B319

(S) -Phe-A110/B319 is a selective binde that has 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex[1].

C62H57F3N8O14S

1227.22

O=C(NCCC(N[C@H](CC(N[C@H](CCCCNC(NC(C=C1)=CC(C(O2)=O)=C1C32C4=C(OC5=CC(O)=CC=C53)C=C(C=C4)O)=S)C(O)=O)=O)C(O)=O)=O)[C@@H](NC(C6=CC=C7N=C(C(C)=NC7=C6)C)=O)CC8=CC=C(C=C8)C9=CC=C(C=C9C)OC(F)(F)F

PI3K

10 mM in DMSO

Room temperature