(S, R, S) -AHPC-PEG2-C4-Cl [CAS 1835705-57-1]

(S, R, S) -AHPC-PEG2-C4-Cl (VH032-PEG2-C4-Cl) is a conjugate of ligands for E3 and 13-atom-length linker. The connector of linker is Halogen group. (S, R, S) -AHPC-PEG2-C4-Cl incorporates the (S, R, S) -AHPC based VHL ligand and an alkyl/ether-based linker. (S, R, S) -AHPC-PEG2-C4-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].

[1835705-57-1]

C32H47ClN4O6S

651.26

O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCCCCCCl)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2

E3 Ligase Ligand-Linker Conjugates

Von Hippel-Lindau (VHL)

98.21

DMSO : ≥ 50 mg/mL|Ethanol : 50 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302-H315-H319-H335

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501