S65487 (sulfate) [CAS 2416937-01-2]
S65487 (sulfate) [CAS 2416937-01-2]
SKU:QM-0075861-01
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Product Details
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Description
S65487 (VOB560) sulfate, a potent and selective Bcl-2 inhibitor, is a proagent of S55746. S65487 sulfate is also active on BCL-2 mutations, such as G101V and D103Y. S65487 sulfate has poor affinity with MCL-1, BFL-1 and BCL-XL. S65487 sulfate induces apoptosis and has anticaner activities[1][2].
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CAS Number
[2416937-01-2]
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Molecular Formula
C41H43ClN6O8S
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Molecular Weight
815.33
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Smiles
O=C(C1=C(C)N(C)C(C2=C(C=CC(Cl)=C2)C(N3[C@@H](CC4=CC=CC=C4C3)CN5CCOCC5)=O)=C1)N(C6=CC=C(C=C6)O)C7=C(C)N(C)C(C#N)=C7.O=S(O)(O)=O
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Target
Apoptosis; Bcl-2 Family
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Purity
99.35
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Solubility
DMSO : 135 mg/mL (ultrasonic) |H2O : 1.25 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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S65487 (sulfate) [CAS 2416937-01-2]
S65487 (sulfate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.