SALT629 [CAS 484026-63-3]

SALT629 is an orally active antitubercular agent with potent intramacrophage activity (EC50 = 1.5 μM). sALT629 shows broad-spectrum anti-Mycobacterium tuberculosis (Mtb) activities across four carbon sources, equipotent efficacy against drug-resistant Mtb, and activity against both slow-replicating and nonreplicating Mtb. sALT629 exhibits synergistic activity when combined with oxazolidinone drugs, such as Linezolid and Sutezolid (HY-10392). sALT629 can be used for the research of tuberculosis[1].

[484026-63-3]

C13H17N5O2

275.31

O=C(CN1N=NC(C2=CC=C(C=C2)OCC(C)C)=N1)N

Bacterial

Room temperature