Saquayamycin B [CAS 99260-67-0]

Saquayamycin B (compound 3) is a new angucycline antibiotic. Saquayamycin B has antitumor activities against a human lung (H-460) and a human breast cancer cell line (MCF-7) with GI50 values of 12.2 and 15.2 µM respectively [1].

[99260-67-0]

C43H48O16

820.83

O=C1C[C@@](O[C@H]2CC[C@H](O[C@H]3C=CC([C@H](C)O3)=O)[C@H](C)O2)(C)C[C@]4(O)[C@@]1(O)C(C(C5=CC=C([C@H]6C[C@@]7([H])O[C@](CC([C@H](C)O8)=O)([H])[C@]8([H])O[C@]7([H])[C@@H](C)O6)C(O)=C5C9=O)=O)=C9C=C4

Antibiotic

Room temperature