SAR 97276 [CAS 321915-72-4]

SAR 97276 (Albitiazolium bromide) is an antimalarial agent. SAR 97276 interfers with the phospholipid metabolism of malarial parasites, especially the biosynthesis of phosphatidylcholine (PC) . SAR 97276 enters erythrocytes through the new permeability pathways (NPP) of infected erythrocytes, and is transported into the malarial parasite by a poly-specific cation carrier[1].

[321915-72-4]

C24H42Br2N2O2S2

614.54

OCCC1=C(C)[N+](CCCCCCCCCCCC[N+]2=CSC(CCO)=C2C)=CS1.[Br-].[Br-]

Parasite

98.05

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature