SARS-CoV-2-IN-12 [CAS 2721455-52-1]

SARS-CoV-2-IN-12 (Compound 27) is a potent SARS-CoV-2-related 3C-like protease inhibitor (Ki=32.1 pM) for preventing SARS-CoV-2 viral replication and that could be useful in the research of COVID-19[1].

[2721455-52-1]

C32H42F3N5O9

697.7

COC1=C2C(NC(C(N[C@@H](CC(C)C)C(N[C@H](C(COC([C@H]3CCCN3C)=O)=O)C[C@H]4C(NCC4)=O)=O)=O)=C2)=CC=C1.OC(C(F)(F)F)=O

SARS-CoV

10 mM in DMSO

Room temperature