SARS-CoV-2-IN-16 [CAS 2761911-40-2]

SARS-CoV-2-IN-16 (Compound 12) is a potent SARS-CoV-2 nucleocapsid protein (NPro) inhibitor. SARS-CoV-2-IN-16 exhibits potent anti-viral activity with the EC50 of 3.69 μM. SARS-CoV-2-IN-16 binds to NPro with the low KD value of 7.82 μM, suggesting that SARS-CoV-2-IN-16 is a potent NPro ligand[1].

[2761911-40-2]

C17H20N2O2

284.35

NC(C=CC=C12)=C2N(CC)CC3=C1C=C(OC)C(OC)=C3

SARS-CoV

10 mM in DMSO

Room temperature