SARS-CoV-2 nsp14-IN-9

SARS-CoV-2 nsp14-IN-9 (Compound 4P) is a selective nsp14 inhibitor with an IC50 of 0.20 μM. SARS-CoV-2 nsp14-IN-9 inhibits both mouse hepatitis virus and SARS-CoV-2 replication[1].

C21H20BrN5O3S

502.38

NC1=C2N=CN([C@H]3[C@H](O)[C@H](O)[C@@H](CSCC4=CC=C5C=CC=CC5=C4Br)O3)C2=NC=N1

SARS-CoV

Room temperature