The SARS-CoV-2 S glycoprotein is critical in infection, binding to the ACE2 receptor and allowing viral particles to attach to the host cell membrane. Cleavage of S2/S2′ triggers cell membrane fusion or internalization via endocytosis. Spike glycoprotein, SARS-CoV-2 (Sf9, His) is the recombinant virus-derived Spike glycoprotein, expressed by Sf9 insect cells, with His labeled tag.
