SB24011 [CAS 1497415-41-4]

SB24011 is a STING-TRIM29 interaction inhibitor with a IC50 value of 3.85 μM. SB24011 enhances STING immunity by upregating STING protein levels, thereby enhancing the immunotherapy effect of STING agonists and anti-PD-1 antibodies through systemic anticancer immunity[1].

[1497415-41-4]

C34H38N4O7

614.69

O=C(NC[C@H]1OCCC1)C2=CC=C(N3[C@H](C(C)C)C(N(CC4=CC=C(O)C=C4)C(CC5=CC=C(OC)C=C5)=C3)=O)C([N+]([O-])=O)=C2

STING

99.7

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice