SCH 39304 [CAS 120924-80-3]

SM-8668 is an effective orally active antifungal agent, with median effective doses (ED50) of 0.18, 3.7, and 5.9 mg/kg for systemic candidiasis, aspergillosis, and cryptococcosis in mice, respectively. Pharmacokinetic studies in mice and rats indicate that SM-8668 has a long half-life and a high total exposure. SM-8668 can be used in anti-infective research[1].

[120924-80-3]

C13H15F2N3O3S

331.34

CS([C@@H](C)[C@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O

Fungal

Room temperature