SCH-538415 [CAS 637772-75-9]

SCH-538415 is a novel acyl carrier protein synthase inhibitor isolated from an unknown bacterial microorganism. The structural elucidation of compound 1 was completed by analyzing spectral data including UV, MS and 2D-NMR spectra. Compound 1 showed inhibitory activity in the acyl carrier protein synthase (AcpS) test with an IC50 value of 4.19 μM and exhibited antibacterial activity against Staphylococcus aureus in the agar diffusion test.

[637772-75-9]

C16H14N2O4

298.29

O=C1N(C2=C(C(C)=C1)C(C(C(C)=C3)=C(C2=O)N(C)C3=O)=O)C

Bacterial

Room temperature