SDH-IN-20

SDH-IN-20 (compound A19) is an antifungal agent. SDH-IN-20 against Verticillium dahlia, R. solani with EC50s of less than 3.0 μg/mL, 2.87 μg/mL. SDH-IN-20 exerts its highly antifungal effects by acting as an effective succinate dehydrogenase (SDH) inhibitor with an IC50 of 29.33 μM. SDH-IN-20 adversely impacts the integrity of cell membranes and mycelial morphologies of R. solani[1].

C24H17FN6OS

456.49

FC1=CC=CC=C1NNC(C2=CSC(C(C=C3)=CC=C3NC4=NC=NC5=CC=CC=C54)=N2)=O

Fungal

Room temperature