SDX-7539 [CAS 1631953-52-0]

SDX-7539 is a selective inhibitor for Methionine aminopeptidase type 2 (MetAP2) . SDX-7539 inhibits proliferarion of HUVECs with an IC50 of 120 μM. SDX-7539 exhibits antitumor activity in NSCLC xenograft athymic nude mice[1].

[1631953-52-0]

C23H38N2O5

422.56

[H][C@@]1([C@@H]([C@@H](CC[C@@]12OC2)OC(N[C@@H]3CC[C@@H](N)CC3)=O)OC)[C@]4(O[C@@H]4C/C=C(C)\C)C

MetAP

10 mM in DMSO

Room temperature