1 1

δ-Secretase inhibitor 11 [CAS 842964-18-5]

δ-Secretase inhibitor 11 [CAS 842964-18-5]

Size

QM-0141339-01

£89.13 GBP
Sale Sold out

Request quote or documents

View full details

Product Details

  • Description

    δ-Secretase inhibitor 11 (compound 11) is an orally active, potent, BBB-penetrated, non-toxic, selective and specific δ-secretase inhibitor, with an IC50 of 0.7 μM. δ-Secretase inhibitor 11 interacts with both the active site and allosteric site of δ-secretase. δ-Secretase inhibitor 11 attenuates tau and APP (amyloid precursor protein) cleavage. δ-Secretase inhibitor 11 ameliorates synaptic dysfunction and cognitive impairments in tau P301S and 5XFAD transgenic mouse models. δ-Secretase inhibitor 11 can be used for Alzheimer's disease research[1].

  • CAS Number

    [842964-18-5]

  • Molecular Formula

    C10H12N4O2

  • Molecular Weight

    220.23

  • Smiles

    NC1=CC=C(N2CCOCC2)C3=NON=C31

  • Target

    Amyloid-β; Caspase

  • Isoform

    Caspase 3; Caspase 8

  • Concentration

    10mM

  • Purity

    99.89

  • Solubility

    DMSO : 116.67 mg/mL (ultrasonic)

  • Storage Conditions

    4°C (Powder, protect from light)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H319, H332, H335

  • Precautions

    H319, H332, H335
Learn more
Variant Variant total Quantity Price Variant total
10 mgQM-0141339-01
10 mgQM-0141339-01
£89.13/ea		 £0.00
£89.13/ea £0.00
25 mgQM-0141339-02
25 mgQM-0141339-02
£200.66/ea		 £0.00
£200.66/ea £0.00
50 mgQM-0141339-03
50 mgQM-0141339-03
£307.58/ea		 £0.00
£307.58/ea £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

δ-Secretase inhibitor 11 [CAS 842964-18-5]

δ-Secretase inhibitor 11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.