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γ-Secretase modulator 11 [CAS 2434630-29-0]
γ-Secretase modulator 11 [CAS 2434630-29-0]
SKU:QM-0067513
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Product Details
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Description
γ-Secretase modulator 11 (1o) showed high potency in vitro and brain exposure, inducing brain a β 42 levels were significantly reduced and showed undetectable inhibition of cytochrome P450 enzymes. In addition, compound 1o showed excellent anti cognitive deficit effect in AD model mice.
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CAS Number
[2434630-29-0]
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Molecular Formula
C28H22F2N4O2
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Molecular Weight
484.5
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Smiles
O=C(C1=NC=C(C2=C(C)N=C3C(OCC4=CC=C(C5=CC=C(F)C=C5)C=C4F)=CC=CN32)C=C1)NC
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Target
γ-secretase
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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γ-Secretase modulator 11 [CAS 2434630-29-0]
γ-Secretase modulator 11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.