SEH/AChE-IN-1 [CAS 2490589-08-5]

SEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE) . sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD) [1].

[2490589-08-5]

C29H31ClF3N5O3

590.04

ClC1=CC2=C(C(NCCC(N3CCC(CC3)NC(NC4=CC=C(C=C4)OC(F)(F)F)=O)=O)=C5C(CCCC5)=N2)C=C1

Cholinesterase (ChE)

AChE

10 mM in DMSO

Room temperature