SEH/AChE-IN-2 [CAS 2490589-09-6]

SEH/AChE-IN-2 (Compound 12b) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE) . sEH/AChE-IN-2 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-2 has the potential for the research of Alzheimer's disease (AD) [1].

[2490589-09-6]

C30H33ClF3N5O3

604.06

ClC1=CC2=C(C(NCCCC(N3CCC(CC3)NC(NC4=CC=C(C=C4)OC(F)(F)F)=O)=O)=C5C(CCCC5)=N2)C=C1

Cholinesterase (ChE)

AChE

10 mM in DMSO

Room temperature