Selinexor-d5

Selinexor-d5 (KPT-330-d5) isthe deuterium labeled Selinexor. Selinexor (KPT-330), an analog of KPT-185, is an orally active and selective CRM1 inhibitor[1][2].

C17H6D5F6N7O

448.34

O=C(NNC1=NC([2H])=C([2H])N=C1[2H])/C([2H])=C([2H])\N2N=C(C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)N=C2

CRM1; Isotope-Labeled Compounds

Room temperature