SETD7-IN-1

SETD7-IN-1 (compound 7) is a PFI-2 analogue. SETD7-IN-1 is a substrate and inhibitor of histone lysine methyltransferase SETD7, with an IC50 of 0.96 ± 0.10 µM[1].

C20H24FN3O4S

421.49

FC1=CC(S(=O)(N[C@H](CC2=CC=CC=C2)C(NCCO)=O)=O)=CC3=C1CNCC3

Histone Methyltransferase

10 mM in DMSO

Room temperature