SETDB1-TTD-IN-1 (TFA)

SETDB1-TTD-IN-1 TFA is a potent, selective and endogenous binder competitive ligand of SET domain bifurcated protein 1 tandem tudor domain (SETDB1-TTD) that binds to TTD, with a Kd of 88 nM. SETDB1-TTD-IN-1 TFA increases SETDB1 methyltransferase activity. SETDB1-TTD-IN-1 TFA can be used for the research of biological functions and disease associations of SETDB1-TTD[1][2].

C30H32F3N5O4

583.6

CN1C[C@@H](C2=CC=C(OCC3=CC=CC=C3)C=C2)C[C@@H](NC4=NC5=C(C(N4CC=C)=O)NC=C5)C1.OC(C(F)(F)F)=O

Histone Methyltransferase

SETDB1/KMT2G

99.77

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature