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SKU:QM-0146798-01
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SGI-1027 is a DNA methyltransferase (DNMT) inhibitor, with IC50s of 7.5 μM, 8 μM, and 12.5 μM for DNMT3B, DNMT3A, and DNMT1 with poly (dI-dC) as substrate.
[1020149-73-8]
C27H23N7O
461.52
O=C(NC1=CC=C(NC2=NC(N)=NC(C)=C2)C=C1)C3=CC=C(NC4=CC=NC5=CC=CC=C45)C=C3
Apoptosis; DNA Methyltransferase
DNMT1; DNMT3
10mM
99.92
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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SGI-1027 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.