Name: Shield-1 [CAS 914805-33-7]
Brand: QuantiMol
SKU: QM-0137402-01
Price: 326.5 GBP
Availability: InStock

Product Details

Description
Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD) [1][2][3].
CAS Number
[914805-33-7]
Molecular Formula
C42H56N2O10
Molecular Weight
748.9
Smiles
O=C([C@H]1N(C([C@H](C2=CC(OC)=C(OC)C(OC)=C2)CC)=O)CCCC1)O[C@@H](C3=CC=CC(OCCN4CCOCC4)=C3)CCC5=CC=C(OC)C(OC)=C5
Target
FKBP
Isoform
FKBP12
Purity
99.73
Solubility
DMSO : 67.5 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
-80°C, stored under nitrogen
Shipping Conditions
Dry Ice

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0137402-01	1 mgQM-0137402-01 £326.50/ea	£0.00	Quantity	£326.50/ea	£0.00

5 mgQM-0137402-02	5 mgQM-0137402-02 £639.98/ea	£0.00	Quantity	£639.98/ea	£0.00

10 mgQM-0137402-03	10 mgQM-0137402-03 £991.11/ea	£0.00	Quantity	£991.11/ea	£0.00

10 mM - 1 mLQM-0137402-04	10 mM - 1 mLQM-0137402-04 £1,005.69/ea	£0.00	Quantity	£1,005.69/ea	£0.00

25 mgQM-0137402-05	25 mgQM-0137402-05 £1,581.60/ea	£0.00	Quantity	£1,581.60/ea	£0.00

50 mgQM-0137402-06	50 mgQM-0137402-06 £2,083.39/ea	£0.00	Quantity	£2,083.39/ea	£0.00

100 mgQM-0137402-07	100 mgQM-0137402-07 £2,773.51/ea	£0.00	Quantity	£2,773.51/ea	£0.00

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Shield-1 [CAS 914805-33-7]

Shield-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.