SHP2-D26 isomer-1 [CAS 2740582-16-3]
SHP2-D26 isomer-1 [CAS 2740582-16-3]
SKU:QM-0148678-01
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Product Details
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Description
SHP2-D26 isomer-1 is an isoform of SHP2-D26. SHP2-D26 isomer-1 cannot degrade SHP2 at 3-1000 nM. SHP2-D26 is a PROTAC SHP2 degrader. (Pink: SHP2 ligand (HY-176797) ; Blue: Isomer control of VHL Ligand 14 (HY-150803) ; Black: linker)[2].
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CAS Number
[2740582-16-3]
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Molecular Formula
C56H79ClN12O6S2
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Molecular Weight
1115.89
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Smiles
ClC(C(SC1=NC=C(N2CCC(N)(CC2)C)N=C1N)=CC=C3)=C3NC(CCC(N(CC4)CCN4CCCCCCCCC(N[C@H](C(C)(C)C)C(N5[C@H](C[C@@H](C5)O)C(N[C@@H](C6=CC=C(C7=C(C)N=CS7)C=C6)C)=O)=O)=O)=O)=O
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Target
PROTACs; SHP2
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Isoform
Von Hippel-Lindau (VHL)
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Concentration
10mM
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Purity
99.76
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315-H319-H320
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Precautions
P264-P280-P302+P352-P305+P351+P338-P362
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SHP2-D26 isomer-1 [CAS 2740582-16-3]
SHP2-D26 isomer-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.