Sinomenine [CAS 115-53-7]

Sinomenine, an alkaloid extracted from Sinomenium acutum, is a blocker of the NF-κB activation[1]. Sinomenine also is an activator of μ-opioid receptor[2].

[115-53-7]

C19H23NO4

329.39

OC(C1=C2C[C@@]3([H])[C@](C=C4OC)([H])[C@@]1(CCN3C)CC4=O)=C(C=C2)OC

Apoptosis; Autophagy; NF-κB; Opioid Receptor

μ Opioid Receptor/MOR

10mM

99.96

1M HCl : 25 mg/mL (ultrasonic; adjust pH to 1 with HCl) |DMSO : 50 mg/mL (ultrasonic)

4°C (Powder, protect from light)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335