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Sirt1/2-IN-4 [CAS 2999646-13-6]
Sirt1/2-IN-4 [CAS 2999646-13-6]
SKU:QM-0072001
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Product Details
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Description
Sirt1/2-IN-4 (compound PS3) is a triple inhibitor of SIRT1/2/3 with IC50s of 1.2 μM (SIRT1), 1.9 μM (SIRT2), and 18.6 μM (SIRT3), respsectivley. Sirt1/2-IN-4 completely blocks p53 deacetylation, with potential anti-cancer activity[1].
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CAS Number
[2999646-13-6]
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Molecular Formula
C21H20N4O3S2
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Molecular Weight
440.54
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Smiles
O=S(NC1=CC(SC2=NNC=N2)=C(C3=C1C=CC=C3)O)(C4=C(C)C(C)=C(C)C=C4)=O
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Target
Apoptosis; Sirtuin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Sirt1/2-IN-4 [CAS 2999646-13-6]
Sirt1/2-IN-4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.