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SIS3 [CAS 521984-48-5]

SIS3 [CAS 521984-48-5]

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QM-0143068-01

£101.50 GBP
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Product Details

  • Description

    SIS3 is a potent and selective inhibitor of Smad3 with an IC50 of 3 μM for Smad3 phosphorylation. SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1[1].

  • CAS Number

    [521984-48-5]

  • Molecular Formula

    C28H28ClN3O3

  • Molecular Weight

    489.99

  • Smiles

    [H]Cl.O=C(/C=C/C1=C(N(C2=NC=CC=C21)C)C3=CC=CC=C3)N4CC5=C(CC4)C=C(C(OC)=C5)OC

  • Target

    TGF-beta/Smad

  • Concentration

    10mM

  • Purity

    99.62

  • Solubility

    DMSO : 100 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    4°C (Powder, sealed storage, away from moisture)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
2 mgQM-0143068-01
2 mgQM-0143068-01
£101.50/ea		 £0.00
£101.50/ea £0.00
5 mgQM-0143068-02
5 mgQM-0143068-02
£226.18/ea		 £0.00
£226.18/ea £0.00
10 mM - 1 mLQM-0143068-03
10 mM - 1 mLQM-0143068-03
£239.54/ea		 £0.00
£239.54/ea £0.00
10 mgQM-0143068-04
10 mgQM-0143068-04
£319.73/ea		 £0.00
£319.73/ea £0.00
25 mgQM-0143068-05
25 mgQM-0143068-05
£602.83/ea		 £0.00
£602.83/ea £0.00
50 mgQM-0143068-06
50 mgQM-0143068-06
£865.26/ea		 £0.00
£865.26/ea £0.00
100 mgQM-0143068-07
100 mgQM-0143068-07
£1,206.68/ea		 £0.00
£1,206.68/ea £0.00
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SIS3 [CAS 521984-48-5]

SIS3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.