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SKU:QM-0141025-01
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SJF-8240 (PROTAC 7) is a proteolysis targeting chimera (PROTAC) degrader. SJF-8240 induces polyubiquitination of c-Met and inhibits the proliferation of GTL16 cells (IC50=66.7 nM) [1].
[2230821-68-6]
C58H65F2N7O11S
1106.24
FC1=CC=C(C=C1)NC(C2(C(NC3=CC(F)=C(C=C3)OC4=CC=NC5=C4C=C(C(OCCCOCCCOCCC(N[C@H](C(N6[C@@H](C[C@H](C6)O)C(NCC7=CC=C(C=C7)C8=C(N=CS8)C)=O)=O)C(C)(C)C)=O)=C5)OC)=O)CC2)=O
C-Met/HGFR; PROTACs
99.33
DMSO : ≥ 100 mg/mL
-20°C (Powder, protect from light, stored under nitrogen)
Blue Ice
H302, H315, H319
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SJF-8240 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.