SKF-105809 [CAS 122454-69-7]

SKF-105809 is a dual-action inhibitor of lipoxygenase and COX. SKF-105809 inhibits edema and inflammatory cell infiltration in mouse models of ear, paw, and peritoneum inflammation. SKF-105809 inhibits the production of relevant acute-phase reactive proteins in a mouse model of arthritis. SKF-105809 exhibits analgesic activity in a mouse abdominal contraction test and inhibits ulceration. SKF-105809 can be used in research on inflammatory and immune system diseases such as peritonitis and arthritis[1].

[122454-69-7]

C18H17N3OS

323.41

O=S(C)C1=CC=C(C2=C(C3=CC=NC=C3)N(CCC4)C4=N2)C=C1

COX; Lipoxygenase

Room temperature