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SM-324405 [CAS 677773-91-0]

SM-324405 [CAS 677773-91-0]

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SKU:QM-0136763-01

£232.25 GBP
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  • Description

    SM-324405 is a TLR7 agonistic antedrug (EC50 = 50 nM), with pEC50 values of 7.3 and 6.6 for human TLR7 and Rat TLR7, respectively. SM-324405 is used for immunoresearch of allergic diseases. An antedrug is defined as a locally active compound that is designed to be rapidly metabolized to an inactive form upon entry into the circulation and prevents systemic toxicity by losing its agonistic activity in a plasmatic environment[1][2][3].

  • CAS Number

    [677773-91-0]

  • Molecular Formula

    C19H23N5O4

  • Molecular Weight

    385.42

  • Smiles

    O=C(OC)CC1=CC=CC(CN2C(NC3=C(N)N=C(OCCCC)N=C23)=O)=C1

  • Target

    Toll-like Receptor (TLR)

  • Isoform

    TLR7

  • Purity

    98.52

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0136763-01
5 mgQM-0136763-01
£232.25/ea
£0.00
£232.25/ea £0.00
10 mM - 1 mLQM-0136763-02
10 mM - 1 mLQM-0136763-02
£250.47/ea
£0.00
£250.47/ea £0.00
10 mgQM-0136763-03
10 mgQM-0136763-03
£339.17/ea
£0.00
£339.17/ea £0.00
25 mgQM-0136763-04
25 mgQM-0136763-04
£589.46/ea
£0.00
£589.46/ea £0.00
50 mgQM-0136763-05
50 mgQM-0136763-05
£902.93/ea
£0.00
£902.93/ea £0.00
100 mgQM-0136763-06
100 mgQM-0136763-06
£1,368.28/ea
£0.00
£1,368.28/ea £0.00

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SM-324405 [CAS 677773-91-0]

SM-324405 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.