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SKU:QM-0150337-01
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SMO-IN-2 is a potent smoothened (SMO) inhibitor with an IC50 value of 123.4 nM for hedgehog (Hh) signaling pathway. SMO-IN-2 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity[1].
[1822355-27-0]
C25H25F4N5O2
503.49
O=C(N(C)C1CCN(C(C2=CC=CC=C2NC3=CC=NN3C)=O)CC1)C4=CC=C(F)C=C4C(F)(F)F
Hedgehog; Smo
98.12
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
4°C (Powder, protect from light)
Room Temperature
H302, H315, H319, H335
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SMO-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.