SMU-V18

SMU-V18 is a vesicular stomatitis virus (VSV) inhibitor, with an EC50 of 6.2 μM. SMU-V18 inhibits VSV-GFP fluorescence intensity, viral mRNA/protein expression, and progeny virus replication. SMU-V18 interferes with early viral infection stages, also effective against wild-type VSV (VSV-WT) . SMU-V18 inhibits VSV-GFP in mouse tissues and prolongs survival. SMU-V18 can be used for the study of vesicular stomatitis virus (VSV) infection[1].

C19H12F3N3O3

387.31

O=C(C1=NC(C2=CC=C3OCCOC3=C2)=NC=C1)NC4=CC(F)=C(F)C(F)=C4

VSV

Room temperature