SN32976 [CAS 1246202-11-8]

SN32976 is a potent and selective class I PI3K and mTOR inhibitor with IC50s of 15.1 nM, 461 nM, 110 nM, 134 nM and 194 nM for PI3Kα, PI3Kβ, PI3Kγ, PI3Kδ and mTOR, respectively. SN32976 shows high selectivity among other 442 kinases. SN32976 shows anticancer effects[1].

[1246202-11-8]

C24H33F2N9O4S

581.64

O=S(CCN(C)C)(N1CCN(C2=NC(N3C4=CC=CC(OC)=C4N=C3C(F)F)=NC(N5CCOCC5)=N2)CC1)=O

MTOR; PI3K

MTOR; PI3Kα; PI3Kβ; PI3Kγ; PI3Kδ

99.49

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature