SNIPER (ABL) -013

SNIPER (ABL) -013, conjugating GNF5 (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein with a DC50 of 20 μM[1].

C42H52F3N7O8

839.9

O=C(NCCOCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC1=CC=CC=C1)N)=O)=O)C2=CC=CC(C3=NC=NC(NC4=CC=C(OC(F)(F)F)C=C4)=C3)=C2

Bcr-Abl; SNIPERs

10 mM in DMSO

Room temperature