SNIPER (ABL) -020

SNIPER (ABL) -020, conjugating Dasatinib (ABL inhibitor) to Bestatin (IAP ligand) with a linker, induces the reduction of BCR-ABL protein[1].

C44H59ClN10O8S

923.52

CC1=C(NC(C2=CN=C(NC3=CC(N4CCN(C(COCCOCCOCCNC([C@H](CC(C)C)NC([C@@H](O)[C@@H](CC5=CC=CC=C5)N)=O)=O)=O)CC4)=NC(C)=N3)S2)=O)C(Cl)=CC=C1

Bcr-Abl; SNIPERs

99.79

DMSO : 200 mg/mL (ultrasonic)

-20°C (Powder, stored under nitrogen)

Blue Ice