Socrodeucitinib [CAS 2457365-35-2]

Socrodeucitinib (Compound Example 58) is an orally active and selective tyrosine kinase 2 (TYK2) inhibitor with an IC50 value of 1.41 nM. Socrodeucitinib exerts anti-inflammatory activity by inhibiting TYK2-mediated cytokine signaling pathways and reducing the secretion of inflammatory factors. Socrodeucitinib is promising for research of autoimmune diseases such as psoriasis and inflammatory diseases[1].

[2457365-35-2]

C22H21D3N8O3

451.5

COC1=C(C2=NN(C3CC3)C=N2)C=CC=C1NC4=C(N=NC(NC(C5CC5)=O)=C4)C(NC([2H])([2H])[2H])=O

JAK

Tyk2

Room temperature