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Sorafenib-d3 [CAS 1130115-44-4]
Sorafenib-d3 [CAS 1130115-44-4]
SKU:QM-0081751-01
£365.90 GBP
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Product Details
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Description
Sorafenib-d3 (Donafenib), a deuterated compound of Sorafenib, is the first deuterium-generation tumor suppressor small molecule. Sorafenib is a multikinase inhibitor IC50s of 6 nM, 20 nM, and 22 nM for Raf-1, B-Raf, and VEGFR-3, respectively[1].
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CAS Number
[1130115-44-4]
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Molecular Formula
C21H13D3ClF3N4O3
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Molecular Weight
467.84
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Smiles
O=C(C1=NC=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=C1)NC([2H])([2H])[2H]
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Target
Apoptosis; Autophagy; Ferroptosis; FLT3; Raf; VEGFR
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Purity
99.57
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Sorafenib-d3 [CAS 1130115-44-4]
Sorafenib-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.