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Sorafenib N-oxide [CAS 583840-03-3]
Sorafenib N-oxide [CAS 583840-03-3]
SKU:QM-0144557-01
£438.80 GBP
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Product Details
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Description
Sorafenib N-oxide is an active metabolite of sorafenib. Sorafenib N-oxide is a linear-mixed inhibitor of microsomal CYP3A4, with a Ki of 15 μM[1][2].
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CAS Number
[583840-03-3]
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Molecular Formula
C21H16ClF3N4O4
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Molecular Weight
480.82
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Smiles
O=C(C1=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C=C2)=CC=[N+]1[O-])NC
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Target
Cytochrome P450; Drug Metabolite
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Isoform
CYP3A4
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Purity
99.7
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Hazard Statement
H360, H362, H372, H410
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Precautions
H360, H362, H372, H410
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Sorafenib N-oxide [CAS 583840-03-3]
Sorafenib N-oxide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.